R421A Refrigerant (Non-Ozone-Depleting HFC Replacement for R22)
R421A is a high-efficiency HFC refrigerant blend (R125 / R134a) specifically developed as a direct replacement for R22 in residential and commercial air conditioning and refrigeration systems. With zero Ozone Depletion Potential (ODP) and significantly lower discharge temperatures, R421A extends compressor life while maintaining reliable cooling performance. Importantly, it is compatible with existing mineral, alkylbenzene, and POE oils, eliminating the need for costly lubricant changes during retrofits.
Key Technical Advantages:
Zero ODP for environmentally responsible cooling
No oil change required when replacing R22
Lower discharge temperature reduces compressor stress
Excellent energy efficiency and cooling capacity
Low glide (<1°C) ensures stable system performance
Proven retrofit solution for existing R22 systems
Key Specifications:
| Parameter | Specification |
| Molecular Weight | 111.7 |
| Boiling Point (1atm,°F) | -41.2 |
| Critical Temperature (°F) | 181 |
| Critical Pressure (psia) | 568.4 |
| Purity % ≥ | 99.5 |
| Moisture ppm ≤ | 10 |
| Acidity ppm ≤ | 1 |
| Vapor Residue ppm ≤ | Not Available |
| Ozone Depletion Potential | 0 |
| Global Warming Potential | 2600 |
Industry-Standard Applications:
Residential & commercial air conditioning (ducted & ductless)
Packaged rooftop units
Refrigerated display cases & cold storage
Heat pumps and split systems
Retrofit projects for R22 phase-out compliance
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